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 RDS Standard AbbreviationsThe following list of standard abbreviations may be used without further definition within the text (not the abstract) of your manuscript considered for publication in the RDS. See information for manuscript preparation for further details on the use of abbreviations within abstracts. For a printable version of this list use the 'Print page' link at the end of this page or download the PDF version. Å: angstrom (10-10 m) 
Ab: antibody 
Ag: antigen 
ADP: adenosine diphosphate 
ADPase: adenosine diphosphatase 
AIDS: acquired immunodeficiancy syndrome 
AMP: adenosine monophosphate 
APC: antigen presenting cell 
ATP: adenosine triphosphate 
ATPase: adenosine triphosphatase 
 
BMI: body mass index 
bp: base pair(s) 
BSA: bovine serum albumin 
 
°C: degrees Celsius 
cAMP: cyclic adenosine monophosphate 
cal: calorie(s) 
CD: cluster of differentiation (in combination with numbers, CD1, CD4 etc.) 
cDNA: complementary DNA 
CFA: complete Freund's adjuvant 
Ci: curie(s) 
CI: confidence interval 
CNS: central nervous system 
CoA: coenzyme A 
Con A: concanavalin A 
cpm: counts per minute 
cRNA: complementary RNA 
CSF: colony-stimulating factor 
CTLA: cytotoxic T lymphocyte antigen 
 
Δ: delta (change in) 
Da: dalton(s) 
DEAE: diethylaminoethyl 
DMEM: Dulbecco's modified Eagle's medium 
DMSO: dimethylsulfoxide 
DNA: deoxyribonucleic acid 
DNase: deoxyribonuclease 
DNP: dinitrophenyl 
dpm: disintegrations per minute 
DTT: dithiothreitol 
 
EDTA: ethylenediaminetetraacetic acid 
EGF: epidermal growth factor 
EGTA: ethyleneglycol-bis (β-aminoethyl ether)-N,N'-tetraacetic acid 
ELISA: enzyme-linked immunosorbent assay 
ELISPOT: enzyme-linked immunospot 
 
°F: degrees Fahrenheit 
FAGS: flourescence-activated cell sorter (TM of Becton Dickinson and Co.) 
Fas: FS7-associated cell surface antigen 
FBS: fetal bovine serum 
Fc: crystallizable fragment 
FCS: fetal calf serum 
FFA: free fatty acid 
FGF: fibroblast growth factor 
FITC: flourescein isothiocyanate 
FMLP: formylmethionylleucylphenylalanine 
ft: foot, feet 
 
g: gram(s) 
GAD: glutamic acid decarboxylase 
GAPDH: glyceraldehyde-3-phosphate dehydrogenase 
G-CSF: granulocyte colony-stimulating factor 
GM-CSF: granulocyte-macrophage colony-stimulating factor 
 
h: hour(s) 
HbA1: glycosylated hemoglobin A1 
HBSS: Hank's balanced salt solution 
HDL: high density lipoprotein 
H&E: hematoxylin and eosin stain 
HEPES: N-2-hydroxyethylpiperazine-N'-2-ethane sulfonic acid 
HGF: hepatocyte growth factor 
HIV: human immunodeficiency virus 
HLA: human leucocyte antigen 
HPLC: high-performance liquid chromatography 
 
i.a.: intra-aterial 
IAA: insulin autoantibody 
IA: insulinoma-associated antigen 
IC50: inhibitory concentration of 50% 
ICA: islet cell antibody 
ICAM: intercellular adhesion molecule 
ID50: infective dose of 50% 
IDDM: insulin-dependent diabetes mellitus 
IFN: interferon 
Ig: immunglobulin (also IgE, IgG etc.) 
IGF: insulin-like growth factor 
IL: interleukin (IL-10, IL-12 etc.) 
i.m.: intramuscular 
in.: inch(es) 
IR: insulin receptor 
IU: international unit 
i.v.: intravenous 
 
°K: degree(s) Kelvin 
kb: kilobase(s) 
kcal: kilocalorie(s) 
Ka: association constant 
Kd: dissociation constant 
Ki: inhibition constant 
Km: Michaelis constant 
kDa: kilodalton(s) 
 
 |             | l: liter(s) 
LD50: 50% lethal dose 
LDL: low-density lipoprotein 
LIF: leukemia inhibitory factor 
LPS: lipopolysccharide 
 
m: meter(s) 
μm: micrometer(s) 
μl: microliter(s) 
ml: milliliter(s) 
M-CSF: macrophage colony-stimulating factor 
MEM: minimum essential medium 
MHC: major histocompatibility complex 
min: minute(s) 
mmHg: millimeters of mercury 
mo: month(s) 
MODY: maturity-onset diabetes of the young 
mol: mole(s) 
mol wt: molecular weigth 
MOPS: morpholino propane sulfonic acid 
Mr: relative molecular mass 
mRNA: messenger ribonucleic acid 
 
n: number of subjects in a study group 
NAD: nicotinamide adenine dinucleotide 
NADH: reduced nicotinamide adenine dinucleotide 
NADP: nicotinamide adenine dinucleotide phosphate 
NADPH: reduced nicotinamide adenine dinucleotide phosphate 
NF-κB: nuclear factor κB 
NF: nuclear factor 
NIDDM: non-insulin-dependent diabetes mellitus 
NIH: National Institute of Health (Bethesda, Maryland, USA) 
NK cell: natural killer cell 
NOD: non-obese diabetic (mouse) 
no.: number 
 
P: probability 
PAGE: polyacrylamide gel electrophoresis 
PCR: polymerase chain reaction 
PDGF: platelet-derived growth factor 
PIPES: piperazine-N,N'-bis(2-ethane sulfonic acid) 
PMA: phorbol myristate acetate 
PMSF: phenylmethylsulfonyl floride 
 
RANTES: regulated upon activation, normal T cell expressed and secreted 
RFLP: restriction fragment length polymorphism 
RIA: radioimmunoassay 
RNA: ribonucleic acid 
RNase: ribonuclease 
rpm: revolutions per minute 
rRNA: ribosomal ribonucleic acid 
RT-PCR: reverse transcriptase polymerase chain reaction 
 
s.c.: subcutaneous 
s: second(s) 
SD: standard deviation 
SDS: sodium dodecyl sulfate 
SE: standard error 
SEM: standard error of mean 
SSC: standard saline citrate 
STAT: signal transducer and activator of transcription 
 
t1/2: half-life 
T1D: type 1 diabetes 
T2D: type 2 diabetes 
TBS: Tris-buffered saline 
TCR: T cell receptor 
TGF: transforming growth factor 
Th cell: T helper cell 
TLC: thin layer chromatography 
TNF: tumor necrosis factor 
Tris: Tris(hydroxymethyl)-aminomethane 
tRNA: transfer ribonucleic acid 
 
U: unit(s) 
UV: ultraviolet 
 
V: volt(s) 
VCAM: vascular cell adhesion molecule 
vol: volume 
vs: versus 
 
W: watt(s) 
wk: week 
wt: weigth 
 
yr: year(s) 
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