Original Data

Evaluation of the Finnish Diabetes Risk Score (FINDRISC) as a Screening Tool for the Metabolic Syndrome

Mohsen Janghorbani^1,2, Hoseinali Adineh², Masoud Amini¹

Manuscript submitted January 10, 2014; resubmitted January 20, 2014; accepted February 2, 2014.

Keywords: metabolic syndrome, type 2 diabetes, first-degree relatives, risk score, glucose tolerance

Abstract

OBJECTIVES: Traditionally, the Finnish Diabetes Risk Score (FINDRISC) questionnaire is a screening tool to estimate risk of type 2 diabetes. In this study, we evaluated the ability of FINDRISC to predict the development of the metabolic syndrome (MetS) in an Iranian population without diabetes and MetS. METHODS: A total of 1,010 first-degree relatives of consecutive patients with type 2 diabetes, 30-70 years old (274 men and 736 women), without diabetes and MetS, were examined and followed up over 8.0 ± 1.6 years (mean ± SD) for MetS incidence. The incidence of MetS was examined across quartiles of FINDRISC, and a receiver operating characteristic (ROC) curve was plotted to assess the discrimination. At baseline and through follow-ups, participants underwent a standard 75 g 2-hour oral glucose tolerance test (OGTT). Data for determining FINDRISC were available from each participant. RESULTS: During 8,089 person-years of follow-up, 69 men and 209 women without MetS and diabetes at baseline subsequently developed MetS. The incidence of MetS was 31.4 per 1000 person-years in men and 35.5 in women. The FINDRSC at baseline was significantly associated with MetS evolution. Participants in the top quartile of FINDRISC were 4.4 times more likely to develop MetS than those in the bottom quartile (rate ratio 4.4; 95% CI 2.7-7.0). The area under the ROC curve was 65.0% (95% CI 61.3-68.7). CONCLUSION: The results of this study suggest that FINDRISC can be applied to detect MetS in a high-risk population.

Fulltext: HTML , PDF (210KB)

This article has been cited by other articles:

	Uptake of screening for type 2 diabetes risk in general dental practice; an exploratory study Bould K, Scott SE, Dunne S, Asimakopoulou K Br Dent J 2017. 222(4):293-296
	Relationship between the Finnish Diabetes Risk Score (FINDRISC), vitamin D levels, and insulin resistance in obese subjects Lima-Martinez MM, Arrau C, Jerez S, Paoli M, Gonzalez-Rivas JP, Nieto-Martinez R, Iacobellis G Prim Care Diabetes 2017. 11(1):94-100
	Differentiation of obese patients at moderate or higher Findrisc score based on their atherogenic index Andreeva-Gateva PA, Konsulova P, Orbetzova M, Georgieva-Nikolova R, Tafradjiiska-Hadjiolova R, Angelova V, Voynikov Y, Nikolova I, Simova I Postgrad Med 2016. 128(8):790-796
	Evaluation of the Japanese Metabolic Syndrome Risk Score (JAMRISC): a newly developed questionnaire used as a screening tool for diagnosing metabolic syndrome and insulin resistance in Japan Tan C, Sasagawa Y, Kamo KI, Kukitsu T, Noda S, Ishikawa K, Yamauchi N, Saikawa T, Noro T, Nakamura H, Takahashi F, Sata F, Tada M, Kokai Y Environ Health Prev Med 2016. 21(6):470-479
	Prevalence of undiagnosed diabetes and prediabetes among voluntary blood donors in a tertiary health care setting Ramasamy J, Parthasarathy UK Int J Res Med Sci 2016. 4(7):2569-2575
	Retrospective Assessment of Family Medicine Office Patients in Last Three Years Fidanci I, Eren SÜ, Arslan I, Tekin O DergiPark 2016. 8(3):151-157