Erratum

Erratum to: Adenosine Monophosphate-Activated Protein Kinase (AMPK) as a New Target for Antidiabetic Drugs: A Review on Metabolic, Pharmacological and Chemical Considerations by Gruzman et al., Rev Diabet Stud 2009, 6(1):13-36

Arie Gruzman, Gali Babai, Shlomo Sasson

In the legends to Figures 2 and 3 of the article by Gruzman et al. in the spring issue 2009 of The Review of Diabetic Studies, pages 13-36, the copyright permission for the figures refer to reference [132], and not [135] as published. The references are published below. The correct text for the legend of Figure 2 on page 21 is:

Figure 2. D-Xylose and Compounds 19, 21 and 24 activate AMPK. A: L6 rat myotube cultures were washed and received fresh medium supplemented with 2% (v/v) FCS, 23.0 mM D-glucose supplemented with 20 mM of D-xylose (D-xyl), 5 μM of Compound 19, 150 μM of Compound 21 or 50 μM of Compound 24. These compounds were present in the medium for 40 min, 12 h, 30 min and 2 h, respectively. Control myotubes received the vehicle (V) only. AICAR (4 mM), 100 nM of insulin (Ins) and 0.25 M of D-sorbitol (S) were present for 1h, 20 min and 30 min, respectively. Whole cell lysates were prepared and Western blot analyses were performed with antibodies against AMPKα and pThr¹⁷²-AMPKα. B: Human myotubes were treated as described above and taken for Western blot analysis of AMPKα and pThr¹⁷²-AMPKα. Representative blot and a summary of n = 3 (^* p < 0.05) in comparison with the respective controls. Re-produced with permission from [132].

The correct text for the legend of Figure 3 on page 22 is:

Figure 3. D-Xylose and Compounds 19, 21 and 24 activate AS160. Whole cell content of AS160 and pThr⁶⁴²-AS160 was determined by Western blot analysis in samples that were prepared from L6 myo-tubes, as described in the legend to Figure 1. Representative blot and a summary of n = 3 (^* p < 0.05) in comparison the respective controls. Reproduced with permission from [132].

References

1. Gruzman A, Shamni O, Ben Yakir M, Sandovski D, Elgart A, Alpert E, Cohen G, Hoffman A, Katzhendler Y, Cerasi E, Sasson S. Novel D-xylose derivatives stimulate muscle glucose uptake by activating AMP-activated protein kinase alpha. J Med Chem 2008. 51(24):8096-8108. [DOD] [CrossRef]
2. Lee YS, Kim WS, Kim KH, Yoon MJ, Cho HJ, Shen Y, Ye JM, Lee CH, Oh WK, Kim CT, et al. Berberine, a natu-ral plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006. 55(8):2256-2264. [DOD] [CrossRef]